The approved therapy Uplizna (inebilizumab) may reduce the risk of disease flares in adults with IgG4-related disease (IgG4-RD) who have kidney involvement, according to a new analysis of clinical trial data. The new analysis focuses on a subgroup of patients in the Phase 3 MITIGATE clinical trial…
Discussion
I have lived with immunoglobulin G4-related disease (IgG4-RD) affecting my orbits, or eye sockets, for more than 25 years. It began with recurring eyelid swelling and eventually progressed to double vision. While the eyelid swelling has largely subsided over time, I haven’t seen straight since the 1990s. Around 2018,…
Discussion
Certain immune cell markers appear to closely track disease activity in people with IgG4-related disease (IgG4-RD), a study by researchers in South Korea suggests. The researchers identified a group of plasma cells, a type of antibody-producing B-cell, with increased activity of a gene called NMU and frequent use of…
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