In a proof-of-concept study, a team of scientists in Spain has identified a range of blood markers related to immune responses that may help to track disease activity in people with IgG4-related disease (IgG4-RD). “In this prospective longitudinal study of [untreated] patients with IgG4-RD, [statistical] models identified exploratory associations…
Discussion
Elevated blood levels of an antibody called IgG1, measured alongside a specific ratio to IgG4, can help identify a more severe form of IgG4-related disease (IgG4-RD) marked by widespread organ damage, a new study shows. Because the severity of IgG4-RD varies widely from person to person, researchers say evaluating…
Discussion
Mikulicz disease — a rare pattern of organ involvement linked to IgG4-related disease (IgG4-RD) — is often misunderstood. This deeply disruptive condition is multiglandular, affecting the lacrimal glands (which produce tears), the parotid and submandibular glands (major salivary glands), and the lymphatic chain in the head and neck. When…
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