Most adults ages 50 and older with immunoglobulin G4-related disease (IgG4-RD) have multiple organ involvement, whereas the disease predominantly affects a single organ in patients ages 25 years or younger, according to a study in Argentina. Data also showed that older patients had more pronounced involvement of lymph…
Most people with IgG4-related cholangitis, a form of IgG4-related disease (IgG4-RD) that affects the bile ducts — the tubes that carry the digestive fluid from the liver — responded well to standard glucocorticoid therapy and had favorable long-term survival, according to a study in China. The data also…
IgG4-related sclerosing mesenteritis (IgG4-SM), a rare and often overlooked manifestation of IgG4-related disease (IgG4-RD) treated in many cases by surgery, may respond to less invasive approaches, a study from China found. IgG4-SM is marked by inflammation and scarring of the mesentery, the tissue that anchors the intestines to the…
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