IgG4-related disease (IgG4-RD) can in some cases affect the voice box, causing symptoms such as voice changes and difficulty breathing. These cases can also be difficult to diagnose and treat, a review study highlights. Noting that this rare manifestation of IgG4-RD is likely to go unrecognized, the researchers emphasized…
Discussion
Note: This column describes the author’s own experiences with Rituxan (rituximab) and Uplizna (inebilizumab). Not everyone will have the same response to treatment. Consult your doctor before starting or stopping a therapy. I have immunoglobulin G4-related disease (IgG4-RD) that presents in the orbits. I had eyelid swelling from 1990…
Discussion
In a proof-of-concept clinical trial, the oral treatment candidate zanubrutinib was shown to reduce disease activity for 10 people with hard-to-treat immunoglobulin G4-related disease (IgG4-RD) affecting the tear and salivary glands. Importantly, according to the researchers, zanubrutinib showed disease-controlling potential as a standalone therapy, bypassing the need for…
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