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Featured Articles
Columns

IgG4-RD changed my relationship with my body; nobody prepared me for that

IgG4‑related disease didn’t just infiltrate my organs; it infiltrated my self‑image. It rewrote the way I see myself, the way I move through the world, and the way I feel in my own skin. Chronic illness is usually framed as a medical journey, but I want to acknowledge the…

White blood cells are seen interspersed with red blood cells. in this illustration. Discussion
News

Scientists identify potential blood-based biomarkers of IgG4-RD severity

In a proof-of-concept study, a team of scientists in Spain has identified a range of blood markers related to immune responses that may help to track disease activity in people with IgG4-related disease (IgG4-RD). “In this prospective longitudinal study of [untreated] patients with IgG4-RD, [statistical] models identified exploratory associations…

An eyedropper hovers next to four vials, all partially filled with red liquid. Discussion
News

Blood test combo flags inflammation, organ damage in IgG4-RD

Elevated blood levels of an antibody called IgG1, measured alongside a specific ratio to IgG4, can help identify a more severe form of IgG4-related disease (IgG4-RD) marked by widespread organ damage, a new study shows. Because the severity of IgG4-RD varies widely from person to person, researchers say evaluating…

Featured Topics

  1. After an IgG4-related disease diagnosis: What to expect

  2. Building your IgG4-related disease care team

  3. Condition confusion: Why IgG4-RD is often misdiagnosed

  4. IgG4-related disease steroid side effects: How to cope

  5. Living with IgG4-RD: How to handle symptoms and flares

  6. Managing mental health with IgG4-related disease

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