Researchers in Japan have described the clinical and tissue features of localized-type IgG4-related cholecystitis, a rare form of IgG4-related disease (IgG4-RD) that affects the gallbladder, which may help distinguish it from gallbladder cancer. “Understanding these … features would contribute to a more accurate differential diagnosis from [gallbladder] cancer,” the…
IgG4-related prostatitis — an inflammation of the prostate caused by IgG4-related disease (IgG4-RD) — can be easily mistaken for an enlarged prostate or prostate cancer, making diagnosis challenging, according to a systematic review of published cases to date. Still, data suggested that most men with IgG4-related prostatitis respond well…
Interactions between two specific subsets of immune cells may contribute to disease activity in people with immunoglobulin G4-related disease (IgG4-RD), according to a new study. Researchers speculated that this newly identified immune-related axis could be a potential target for new IgG4-RD treatments. The study, “Extrafollicular [Tph2–CD11c-positive,…
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